PIMS-TS is a rare hyperinflammatory immune response syndrome, usually occurring two to six weeks after SARS-CoV-2 infection, which mainly affects schoolchildren and is often associated with the need for intensive care (2). The most common clinical signs are high fever, gastrointestinal symptoms such as abdominal pain, vomiting and diarrhea, cardiovascular dysfunction (impaired LVEF, hypotension, shock) and neurological symptoms such as headache and encephalopathy (1, 2, 4). The definition criteria include various clinical and laboratory parameters, which vary slightly depending on the authors (4, 6, 7). With intensive care treatment with circulatory support and administration of methylprednisolone, mortality and long-term consequences remain low.
Keyphrases
- immune response
- abdominal pain
- dendritic cells
- case report
- toll like receptor
- early onset
- risk factors
- cardiovascular events
- sleep quality
- depressive symptoms
- coronary artery disease
- physical activity
- clostridium difficile
- combination therapy
- replacement therapy
- preterm birth
- gestational age
- respiratory syndrome coronavirus