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Reference Values to Assess Hemodilution and Warn of Potential False-Negative Minimal Residual Disease Results in Myeloma.

Noemí PuigJuan A Flores-MonteroLeire BurgosMaría-Teresa CedenaLourdes CordónJosé-Juan PérezLuzalba Sanoja-FloresIrene ManriquePaula Rodríguez-OteroLaura RosiñolJoaquin Martinez LopezMaria-Victoria Mateos-MantecaJuan-José LahuertaJoan BladéJesús San F MiguelAlberto OrfaoJuan José Lahuerta
Published in: Cancers (2021)
Our study supports the routine assessment of BM cellularity to evaluate hemodilution, since reduced BM-specific cell types as compared to reference values (either treatment-specific or from HA if the former are unavailable) could indicate hemodilution and a false-negative MRD result.
Keyphrases
  • single cell
  • cell therapy
  • multiple myeloma
  • stem cells
  • human health
  • replacement therapy