Mapping microarchitectural degeneration in the dilated ascending aorta with ex vivo diffusion tensor imaging.
Mofei WangJustin A Ching-JohnsonHao YinCaroline O'NeilAlex X LiMichael W A ChuRobert BarthaJ Geoffrey PickeringPublished in: European heart journal open (2023)
high-field DTI can detect ascending aorta medial degeneration and can differentiate TAAs in accordance with their histopathology, especially elastin and GAG changes. This non-destructive window into aortic medial microstructure raises prospects for probing the risks of TAAs beyond lumen dimensions.
Keyphrases
- pulmonary artery
- aortic dissection
- coronary artery
- white matter
- aortic valve
- pulmonary hypertension
- pulmonary arterial hypertension
- high resolution
- human health
- current status
- ultrasound guided
- molecular dynamics simulations
- multiple sclerosis
- high density
- risk assessment
- mass spectrometry
- climate change
- atrial fibrillation