Targeting Autophagy With the Synergistic Combination of Chloroquine and Rapamycin as a Novel Effective Treatment for Well-differentiated Liposarcoma.
Noriyuki MasakiYusuke AokiKoya ObaraYutaro KubotaMichael BouvetJun MiyazakiRobert M Hoffman
Published in: Cancer genomics & proteomics (2023)
The combination of RAPA and CQ increased the number of autophagosomes which led to apoptosis in 93T449 WDLS cells, suggesting novel effective treatment for this recalcitrant cancer by targeting autophagy.