Safety and Preliminary Efficacy of Pembrolizumab Following Transarterial Chemoembolization for Hepatocellular Carcinoma: The PETAL Phase Ib Study.

David James Pinato Antonio D'Alessio Claudia Angela Maria Fulgenzi Alexandra Emilia Schlaak Ciro Celsa Saskia Killmer Jesus Miguens Blanco Caroline Ward Charalampos-Vlasios Stikas Openshaw M R Nicole Acuti Georgios Nteliopoulos Cristina Balcells Hector C Keun Robert D Goldin Paul J Ross Alessio Cortellini Robert Thomas Anna Mary Young Nathan P Danckert Paul Tait Julian R Marchesi Bertram Bengsch Rohini Sharma

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)

TACE plus pembrolizumab was tolerable with no evidence of synergistic toxicity, encouraging further clinical development of immunotherapy alongside TACE.

Keyphrases

advanced non small cell lung cancer
radiofrequency ablation
oxidative stress
drug delivery