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Novel insights into the assessment of risk of upper gastrointestinal bleeding in decompensated cirrhotic children.

Nicolas BonnetJérôme PaulThibault HelleputteFrancis VeyckemansThierry PirotteCaroline PrégardienStéphane EeckhoudtCédric HermansThierry DetaillePhilippe ClapuytRenaud MentenDana DumitriuRaymond RedingIsabelle ScheersSharat VarmaFrançoise SmetsEtienne SokalXavier Stéphenne
Published in: Pediatric transplantation (2019)
We demonstrated an association between hemostatic factors and the upper gastrointestinal bleeding risk. A low fibrinogen level and platelet aggregation dysfunction may predict the risk of bleeding in children with decompensated cirrhosis. A predictive model is available to assess the upper gastrointestinal bleeding risk but needs further investigations. Clinicaltrials.gov number: NCT03244332.
Keyphrases
  • heart failure
  • young adults
  • oxidative stress
  • ejection fraction
  • liver failure
  • hepatitis b virus
  • clinical evaluation