The expansion and severity of chronic MS lesions follows a periventricular gradient.
Samuel KlistornerMichael Harry BarnettStuart L GrahamChenyu WangAlexander KlistornerPublished in: Multiple sclerosis (Houndmills, Basingstoke, England) (2022)
Our data suggest that chronic white matter lesions in close proximity to the ventricles are more destructive, show a higher degree of expansion at the lesion border and accelerated tissue loss in the lesion core.