Human Leukocyte Antigen B14:01 and B35:01 Are Associated With Trimethoprim-Sulfamethoxazole Induced Liver Injury.

Yi Ju Li Elizabeth Jane Phillips Andrew DellingerPaola NicolettiRyan SchutteDanmeng LiDavid A OstrovRobert J FontanaPaul B WatkinsAndrew StolzAnn K DalyGuruprasad P AithalHuiman BarnhartNaga Chalasaninull null

Published in: Hepatology (Baltimore, Md.) (2021)

HLA-B*14:01 is associated with TMP-SMX DILI in European Americans, and HLA-B*35:01 may be a potential genetic risk factor for African Americans.

Keyphrases

endothelial cells
drug induced
induced pluripotent stem cells
genome wide
peripheral blood
dna methylation
antibiotic resistance genes
microbial community