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Novel predictors of immune checkpoint inhibitor response and prognosis in advanced non-small-cell lung cancer with bone metastasis.

Yohei AsanoNorio YamamotoSatoru DemuraKatsuhiro HayashiAkihiko TakeuchiSatoshi KatoShinji MiwaKentaro IgarashiTakashi HiguchiYuta TaniguchiSei MorinagaTakashi SoneMiho OkudaIsao MatsumotoSeiji YanoHiroyuki Tsuchiya
Published in: Cancer medicine (2023)
This study identified some novel predictors for favorable therapeutic response and prognosis in advanced NSCLC patients with bone metastases undergoing ICI treatment. Pretreatment NLR less than 2.1 can be considered the most important predictor.
Keyphrases
  • advanced non small cell lung cancer
  • epidermal growth factor receptor
  • small cell lung cancer
  • bone mineral density
  • soft tissue
  • tyrosine kinase
  • bone regeneration