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Frailty, lifestyle, genetics and dementia risk.

David D WardJanice M RansonLindsay M K WallaceDavid J LlewellynKenneth Rockwood
Published in: Journal of neurology, neurosurgery, and psychiatry (2021)
Frailty is strongly associated with dementia risk and affects the risk attributable to genetic factors. Frailty should be considered an important modifiable risk factor for dementia and a target for dementia prevention strategies, even among people at high genetic risk.
Keyphrases
  • mild cognitive impairment
  • cognitive impairment
  • genome wide
  • metabolic syndrome
  • type diabetes
  • physical activity
  • dna methylation
  • weight loss