Pre-clinical evaluation of biomarkers for the early detection of nephrotoxicity following alpha-particle radioligand therapy.

Mengshi LiClaudia Robles-PlanellsDijie LiuStephen A GravesGabriela Vasquez-MartinezGabriel Mayoral-AndradeDongyoul LeePrerna RastogiBrenna M MarksEdwin A SagastumeRobert M WeissSarah C Linn-PeiranoFrances L JohnsonMichael K SchultzDiana Zepeda-Orozco

Published in: European journal of nuclear medicine and molecular imaging (2023)

Urine NGAL secretion could be a potential early diagnostic tool to identify unrecognized tubular damage and predict long-term α-RLT-related nephrotoxicity.

Keyphrases

clinical evaluation
drug induced
oxidative stress
human health
climate change