Autozygosity islands and ROH patterns in Nellore lineages: evidence of selection for functionally important traits.
Elisa PeripolliJulia MetzgerMarcos Vinícius Antunes de LemosNedenia Bonvino StafuzzaSabrina KluskaBianca Ferreira OlivieriFabieli Louise Braga FeitosaMariana Piatto BertonFernando Brito LopesDanísio Prado MunariRaysildo Barbosa LôboCláudio de Ulhoa MagnaboscoFernando Di CroceJason OsterstockSue DeniseAngélica Simone Cravo PereiraFernando BaldiPublished in: BMC genomics (2018)
Low FPED-FROH correlation estimates indicate that FPED is not the most suitable method for capturing ancient inbreeding when the pedigree does not extend back many generations and FROH should be used instead. Enriched terms (p < 0.01) suggest a strong selection for immune response. Non-overlapping islands within the lineages greatly explain the mechanism underlying selection for functionally important traits in Nellore cattle.