β cell replacement therapy for the cure of diabetes.

Published in: Journal of diabetes investigation (2022)

Islet transplantation is an important option in the treatment of type 1 diabetes. However, a donor shortage and immunosuppressant-related complications are the current major hurdles of islet transplantation. In this review, we discuss recent updates on islet transplantation to overcome these current obstacles and we share our perspectives on future β cell replacement therapy.

Keyphrases

replacement therapy
type diabetes
cell therapy
smoking cessation
single cell
cardiovascular disease
glycemic control
stem cells
mesenchymal stem cells
metabolic syndrome
risk factors
adipose tissue
current status
combination therapy