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Bipartite graph-based collaborative matrix factorization method for predicting miRNA-disease associations.

Feng ZhouMeng-Meng YinCui-Na JiaoZhen CuiJing-Xiu ZhaoJin-Xing Liu
Published in: BMC bioinformatics (2021)
Five-fold cross-validation is used to evaluate the capabilities of our method. Simulation experiments are implemented to predict new MDAs. More importantly, the AUC value of our method is higher than those of some state-of-the-art methods. Finally, many associations between new miRNAs and new diseases are successfully predicted by performing simulation experiments, indicating that BGCMF is a useful method to predict more potential miRNAs with roles in various diseases.
Keyphrases
  • climate change
  • convolutional neural network
  • human health