Dysregulated T helper type 1 (Th1) and Th17 responses in elderly hospitalised patients with infection and sepsis.

John D CoakleyEamon P BreenAna Moreno-OliveraAlhanouf I Al-HarbiAshanty M MeloBrian O'ConnellRoss McManusDerek G DohertyThomas Ryan

Published in: PloS one (2019)

Persistent failure of T cell activation was observed in patients with sepsis. Sepsis was associated with attenuated CD8+Th1 and CD4+Th17 based lymphocyte response.

Keyphrases

septic shock
acute kidney injury
intensive care unit
dendritic cells
middle aged
community dwelling