Inactivated Nevus Tissue with High Hydrostatic Pressure Treatment Used as a Dermal Substitute after a 28-Day Cryopreservation Period.

Yoshitaka MatsuuraMichiharu SakamotoShuichi OginoJun ArataNaoki Morimoto

Published in: BioMed research international (2021)

Cryopreservation at -30°C for 28 days did not result in significant damage to inactivated nevus tissue, and applied CE on the cryopreserved nevus tissues took and regenerated the epidermis. Inactivated nevus tissue with HHP can be used as a dermal substitute after 28-day cryopreservation.

Keyphrases

gene expression
oxidative stress
bone marrow
mesenchymal stem cells
combination therapy