A New Medical Record Proposal to the Prognostic Risk Assessment for MRONJ in Oncologic Patients: "Sapienza Head and Neck Unit" Proposal.
Edoardo BraunerSilvia MeziAlessandro CiolfiChiara CiolfiResi PucciAndrea CassoniAndrea BattistiGabriele PiescoFrancesca De FeliceNicola PrannoMatteo ArmidaFrancesca De AngelisUmberto RomeoMauro CapocciGianluca TenoreVincenzo TomboliniValentino ValentiniLivia OttolenghiAntonella PolimeniStefano Di CarloPublished in: International journal of environmental research and public health (2021)
Medication-related osteonecrosis of the jaw (MRONJ) is an adverse event associated with antiresorptive and antiangiogenic drugs. The use of these drugs in the treatment of cancer patients with bone metastasis is necessary and standardized in the literature. A multidisciplinary approach for the patient's management is strongly recommended. Therefore, it should be necessary to integrate the path of these subjects with a dedicated dental screening in order to first assess the individual risk of developing a MRONJ, and then to plan dental treatments and oral hygiene sessions, and finally to schedule a follow-up to intercept and treat early osteonecrosis. The aim of this manuscript is to propose a new simple medical report to evaluate patients affected by metastatic bone cancer in order to reduce the risk of developing MRONJ.
Keyphrases
- end stage renal disease
- risk assessment
- newly diagnosed
- healthcare
- chronic kidney disease
- ejection fraction
- peritoneal dialysis
- squamous cell carcinoma
- systematic review
- prostate cancer
- bone mineral density
- prognostic factors
- emergency department
- heavy metals
- oral health
- squamous cell
- postmenopausal women
- quality improvement
- bone loss
- young adults
- drug induced
- bone regeneration
- adverse drug
- soft tissue