Possible recombination between two variants of concern in a COVID-19 patient.

Yaqing HeWentai MaShengyuan DangLong ChenRenli ZhangShujiang MeiXinyi WeiQiuying LvBo PengJiancheng ChenDongfeng KongYing SunXiujuan TangWeihua WuZhigao ChenShimin LiJia WanXuan ZouMingkun LiTiejian FengLili Ren Jianwei Wang

Published in: Emerging microbes & infections (2022)

We identified an individual who was coinfected with two SARS-CoV-2 variants of concern, the Beta and Delta variants. The ratio of the relative abundance between the two variants was maintained at 1:9 (Beta:Delta) in 14 days. Furthermore, possible evidence of recombinations in the Orf1ab and Spike genes was found.

Keyphrases

sars cov
copy number
coronavirus disease
genome wide
respiratory syndrome coronavirus
dna damage
case report
gene expression
dna repair
transcription factor