Characteristics associated with poor COVID-19 outcomes in people with psoriasis, psoriatic arthritis and axial spondyloarthritis: data from the COVID-19 PsoProtect and Global Rheumatology Alliance physician-reported registries.
Pedro M MachadoMartin SchaeferSatveer K MahilJean LiewLaure GossecNick DandAlexander PfeilAnja StrangfeldAnne Constanze RegiererBruno FautrelCarla Gimena AlonsoCarla G S SaadChristopher E M GriffithsClaudia LomaterCorinne Miceli-RichardDaniel WendlingDeshiré Alpizar-RodriguezDieter WiekElsa F MateusEmily SirotichEnrique Roberto SorianoFrancinne Machado RibeiroFelipe OmuraFrederico Rajão MartinsHelena SantosJonathan DauJonathan N BarkerJonathan S HausmannKimmie L HyrichLianne GenslerLigia SilvaLindsay JacobsohnLoreto CarmonaEdgard Torres Dos Reis-NetoMarcos David ZelayaMaría de Los Ángeles SeverinaMark YatesMaureen DubreuilMonique Gore-MassyNicoletta RomeoNigil HaroonPaul SufkaRebecca GraingerRebecca HasseliSaskia Lawson-ToveySuleman BhanaThao PhamTor OlofssonWilson Bautista-MolanoZachary S WallaceZenas Z N YiuJinoos YazdanyPhilip C RobinsonCatherine H SmithPublished in: Annals of the rheumatic diseases (2023)
Older age, male sex, comorbidity burden, higher disease activity and glucocorticoid intake were associated with more severe COVID-19. Later pandemic time periods, PsO and exposure to TNFi, IL17i and IL-23i/IL-12+23i were associated with less severe COVID-19. These findings will enable risk stratification and inform management decisions for patients with PsO, PsA and axSpA during COVID-19 waves or similar future respiratory pandemics.
Keyphrases
- coronavirus disease
- sars cov
- disease activity
- systemic lupus erythematosus
- rheumatoid arthritis
- ankylosing spondylitis
- respiratory syndrome coronavirus
- juvenile idiopathic arthritis
- prostate cancer
- emergency department
- primary care
- early onset
- type diabetes
- adipose tissue
- electronic health record
- weight gain
- data analysis