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NLRP7 Enhances Choriocarcinoma Cell Survival and Camouflage in an Inflammasome Independent Pathway.

Déborah ReynaudNadia AlfaidyConstance ColletNicolas LemaitreFrederic SergentCéline MiegeEmmanuelle SoleilhacAlaa Al AssiPadma MurthiGilles CourtoisMarie-Odile FauvarqueRima SlimMohamed BenharougaRoland Abi Nahed
Published in: Cells (2023)
This study demonstrates for the first time the mechanism by which NLRP7, independently of its inflammasome machinery, contributes to GC growth and tumorigenesis. The clinical relevance of NLRP7 in this rare cancer highlights its potential therapeutic promise as a molecular target to treat resistant GC patients.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • nlrp inflammasome
  • chronic kidney disease
  • papillary thyroid
  • gas chromatography
  • patient reported outcomes
  • big data
  • deep learning
  • artificial intelligence
  • single molecule