MANP (M-Atrial Natriuretic Peptide) Reduces Blood Pressure and Furosemide-Induced Increase in Aldosterone in Hypertension.

Nina A DzhoyashviliSeethalakshmi R IyerHorng H ChenJohn C Burnett

Published in: Hypertension (Dallas, Tex. : 1979) (2022)

We provide novel evidence that MANP potentiates the BP-lowering actions of furosemide, suppresses the activation of renin-angiotensin-aldosterone system, and preserves renal function. These data are highly relevant to clinical needs in the treatment of hypertension and heart failure.

Keyphrases

blood pressure
angiotensin ii
heart failure
angiotensin converting enzyme
hypertensive patients
heart rate
atrial fibrillation
electronic health record
big data
left atrial
blood glucose
drug induced
oxidative stress
combination therapy
replacement therapy
weight loss
insulin resistance
acute heart failure