The role of motor proteins in photoreceptor protein transport and visual function.
Rakesh RadhakrishnanVenkateshwara R DronamrajuMatthias LeungAndrew GruesenAshish Kumar SolankiStephen WalterhouseHeidi RoehrichGrace SongRafael da Costa MonsantoSebahattin CureogluRené MartinAltaf A KondkarFrederik J van KuijkSandra R MontezumaHans-Joachim KnöelkerRobert B HufnagelGlenn P LoboPublished in: Ophthalmic genetics (2022)
Our mini-review will discuss mechanisms of protein transport within photoreceptors and introduce a novel role for an unconventional motor protein, MYO1C, in actin-based motor transport of the visual chromophore Rhodopsin to the OS, in support of phototransduction and visual function.