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Clinical outcomes of sofosbuvir-based antivirals in patients with COVID-19: a systematic review and meta-analysis of randomized trials.

Chia Siang Chia KowAmaan JavedDinesh Sangarran RamachandramSyed Shahzad Hasan
Published in: Expert review of anti-infective therapy (2021)
Sofosbuvir-based direct-acting antiviral agents have no protective effects against the development of severe illness in patients with COVID-19 with the current dosing regimen. Whether sofosbuvir-based direct-acting antiviral agents could offer mortality benefits would require further investigations.
Keyphrases
  • hepatitis c virus
  • hepatitis c virus infection
  • cardiovascular events
  • type diabetes
  • coronary artery disease