Cohort profile: the Utrecht Cardiovascular Cohort-Second Manifestations of Arterial Disease (UCC-SMART) Study-an ongoing prospective cohort study of patients at high cardiovascular risk in the Netherlands.
Maria C CastelijnsMarga A G HelminkSteven H J HagemanFolkert W AsselbergsGert J de BorstMichiel L BotsMaarten J CramerJannick A N DorresteijnMarielle H Emmelot-VonkMirjam I GeerlingsPim A de JongNiels P van der KaaijL Jaap KappelleA Titia LelyManon G van der MeerBarend M MolHendrik M NathoeN Charlotte Onland-MoretRutger B van PetersenYnte M RuigrokMaarten van SmedenMartin TeraaAngela VandersteenMarianne C VerhaarJan WesterinkFrank L J VisserenPublished in: BMJ open (2023)
The UCC-SMART Study guarantees an infrastructure for research in patients at high cardiovascular risk. The cohort will continue to include about 600 patients yearly and follow-up will be ongoing to ensure an up-to-date cohort in accordance with current healthcare and scientific knowledge. In the near future, UCC-SMART will be enriched by echocardiography, and a food frequency questionnaire at baseline enabling the assessment of associations between nutrition and CVD and diabetes.