Clinical and Magnetic Resonance Imaging Outcome Predictors in Pediatric Anti-N-Methyl-D-Aspartate Receptor Encephalitis.
Frederik BartelsStephan KrohnMarc NikolausJessika JohannsenRonny WickströmMareike SchimmelMartin HäuslerAndrea BergerMarkus BreuMarkus BlankenburgJohannes StoffelsOliver HendricksGünther BernertGerd KurlemannEllen KnierimAngela KaindlKevin RostásyCarsten FinkePublished in: Annals of neurology (2020)
Children with NMDARE exhibit significant brain volume loss and failure of age-expected brain growth. Abnormal MRI findings, a clinical presentation with sensorimotor deficits, and a treatment delay > 4 weeks are associated with worse clinical outcome. These characteristics represent promising prognostic biomarkers in pediatric NMDARE. ANN NEUROL 2020 ANN NEUROL 2020;88:148-159.