Early management of acute severe UC in the biologics era: development and international validation of a prognostic clinical index to predict steroid response.
Alex AdamsVipin GuptaWaled MohsenThomas P ChapmanDeloshaan SubhaharanPradeep Kakkadasam RamaswamySudheer Kumar VuyyuruSaurabh KediaColleen Gc McGregorAlison SimmonsBruce D GeorgeRebecca PalmerOliver BrainAlissa WalshVineet AhujaSimon P L TravisJack SatsangiPublished in: Gut (2022)
Emergency colectomy rates for ASC have halved in 25 years to 8%-15% worldwide. Patients who will not respond to corticosteroids are readily identified on admission and may be prioritised for early intensification of therapy.