The Effects of Colchicum Dispert and Bone Marrow-Derived Mesenchymal Stem Cell Therapy on Skeletal Muscle Injury in a Rat Aortic Ischemia-Reperfusion Model.
Atilla OrhanÖmer Faruk ÇiçekBahadır ÖztürkHakan AkbayrakNejat ÜnlükalHakan VatansevMerve SolmazMustafa BüyükateşSeda AniçFadime OvalıEissa AlmaghrebiFatma AkatHusamettin VatansevPublished in: Journal of cardiovascular development and disease (2024)
This study highlights the potential of using combined colchicine and mesenchymal stem cell therapy to reduce muscle damage caused by ischemia-reperfusion injury. Further research is needed to understand the underlying mechanisms and confirm the clinical significance of this approach in treating extremity ischemia-reperfusion injuries.
Keyphrases
- cell therapy
- stem cells
- skeletal muscle
- mesenchymal stem cells
- ischemia reperfusion injury
- oxidative stress
- bone marrow
- insulin resistance
- aortic valve
- left ventricular
- pulmonary artery
- metabolic syndrome
- type diabetes
- heart failure
- risk assessment
- pulmonary hypertension
- pulmonary arterial hypertension
- aortic dissection