Downregulation of exosomal CLEC3B in hepatocellular carcinoma promotes metastasis and angiogenesis via AMPK and VEGF signals.

Wenjuan DaiYilin WangTianxiao YangJing WangWeicheng WuJianxin Gu

Published in: Cell communication and signaling : CCS (2019)

This study demonstrates that CLEC3B acts as a novel independent prognostic factor, and CLEC3B in exosomes might be a potential therapeutic target for hepatocellular carcinoma.

Keyphrases

prognostic factors
endothelial cells
vascular endothelial growth factor
stem cells
mesenchymal stem cells
cell proliferation
skeletal muscle
risk assessment
human health
protein kinase