Changes in tophus composition during urate-lowering therapy: a dual energy CT study.

Leanne ChenGreg GambleAnne HorneJill DrakeAnthony J DoyleTill Uhlig Lisa K Stamp Nicola Dalbeth

Published in: Arthritis care & research (2023)

The composition of the tophus is dynamic and changes during urate-lowering therapy for gout management. The soft tissue component of the tophus is slower to respond and may persist without measurable MSU crystal deposition.

Keyphrases

dual energy
computed tomography
image quality
soft tissue
contrast enhanced
uric acid
magnetic resonance imaging
positron emission tomography
stem cells
bone marrow
mesenchymal stem cells