Development of Parkinson Disease and Its Relationship with Incidentally Discovered White Matter Disease and Covert Brain Infarction in a Real-World Cohort.
David M KentLester Y LeungEric J PuttockAndy Y WangPatrick H LuetmerDavid F KallmesJason NelsonSunyang FuChengyi ZhengEllen M VickeryHongfang LiuAlastair J NoyceWansu ChenPublished in: Annals of neurology (2022)
Incidentally discovered white matter disease was associated with subsequent Parkinson disease, an association strengthened with younger age and increased white matter disease severity. Incidentally discovered covert brain infarction did not appear to be associated with subsequent Parkinson disease. ANN NEUROL 2022;92:620-630.