Elucidating Pathways Mediating the Relationship Between Male Sex and COVID-19 Severity.
Randy M StalterVidya AtluriFan XiaKatherine K ThomasKristine F LanAlexander L GreningerRena C PatelPublished in: Clinical epidemiology (2022)
Males appear to be at higher risk at all steps of the continuum of COVID-19 illness. The strongest mediating signal, albeit non-significant, is with inflammatory pathways. Further elucidation of causal pathways linking sex and COVID-19 severity is needed in larger cohorts.