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The safety of isoniazid tuberculosis preventive treatment in pregnant and postpartum women: systematic review and meta-analysis.

Yohhei HamadaCarmen FigueroaMario Martín-SánchezDennis FalzonAvinash Kanchar
Published in: The European respiratory journal (2020)
We found inconsistent associations between IPT and adverse pregnancy outcomes. Considering the grave consequences of active TB in pregnancy, current evidence does not support systematic deferral of IPT until postpartum. Research on safety is needed.
Keyphrases
  • pregnancy outcomes
  • pregnant women
  • mycobacterium tuberculosis
  • pulmonary tuberculosis
  • adipose tissue
  • metabolic syndrome
  • hiv aids
  • polycystic ovary syndrome
  • combination therapy