Mycobacterium bovis BCG-mediated suppression of Th17 response in mouse experimental autoimmune encephalomyelitis.

Goro MatsuzakiNaoko TeruyaHideyasu Kiyohara KohamaKeiko AraiYukihiro ShibuyaYasushi ChumaKazuhiro Matsuo

Published in: Immunopharmacology and immunotoxicology (2021)

The results suggest that BCG inoculation suppresses the Th17 response in the CNS of EAE mice via a mechanism that may involve the suppression of egress of encephalitogenic T cells from lymphoid organs.

Keyphrases

mycobacterium tuberculosis
signaling pathway
blood brain barrier
type diabetes
metabolic syndrome
adipose tissue