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Quantity and quality of nucleic acids extracted from archival formalin fixed paraffin embedded prostate biopsies.

Jessica CarlssonSabina DavidssonJonna FridfeldtFrancesca GiunchiValentina FianoChiara GrassoRenata ZelicLorenzo RichiardiOve AndrénAndreas PetterssonMichelangelo FiorentinoOlof Akre
Published in: BMC medical research methodology (2018)
To conclude, this study shows that the choice of nucleic acid extraction kit affects the quantity and quality of extracted products. Furthermore, we show that extraction of nucleic acids from archival formalin-fixed prostate biopsies is possible, allowing molecular studies to be performed on this valuable sample collection.
Keyphrases
  • nucleic acid
  • prostate cancer
  • benign prostatic hyperplasia
  • quality improvement
  • ultrasound guided
  • decision making
  • case control