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Hepatitis B virus X protein induces ALDH2 ubiquitin-dependent degradation to enhance alcoholic steatohepatitis.

Haoxiong ZhouSizhe WanYujun LuoHuiling LiuJie JiangYunwei GuoJia XiaoBin Wu
Published in: Gastroenterology report (2023)
Our study demonstrated that HBx-induced ubiquitin-dependent degradation of mitochondrial ALDH2 aggravates alcoholic steatohepatitis.
Keyphrases
  • hepatitis b virus
  • liver injury
  • drug induced
  • liver failure
  • small molecule
  • oxidative stress
  • high glucose
  • diabetic rats
  • protein protein
  • amino acid
  • binding protein
  • stress induced