Hepatitis B virus X protein induces ALDH2 ubiquitin-dependent degradation to enhance alcoholic steatohepatitis.
Haoxiong ZhouSizhe WanYujun LuoHuiling LiuJie JiangYunwei GuoJia XiaoBin WuPublished in: Gastroenterology report (2023)
Our study demonstrated that HBx-induced ubiquitin-dependent degradation of mitochondrial ALDH2 aggravates alcoholic steatohepatitis.