Widely heterogeneous humoral and cellular immunity after mild SARS-CoV-2 infection in a homogeneous population of healthy young men.
Nina Le BertWan Ni ChiaWei Yee WanAlvin Kuo Jing TeoSamuel Zeng-Rong ChongNicole TanDoreen Soek Chin TanAdeline ChiaIain Beehuat TanKamini KunasegaranQin Xuan ChuaMohammad Yazid AbdadAven Shan Hua NgShawn VasooJulian Xiao-Li AngMao Sheng LeeLouisa SunJinyan FangFeng ZhuAlex R CookTar Choon AwJingxiang HuangClarence C TamFong Sin LeeHannah ClaphamEnan Jun-Kang GohMonica Socheata Suor PeouShiow Pin TanSiew Kim OngLin-Fa WangAntonio BertolettiLi Yang HsuBiauw Chi OngPublished in: Emerging microbes & infections (2021)
Humoral and cellular immunity against SARS-CoV-2 is induced with differing kinetics of persistence in those with mild disease. The magnitude of T cells and antibodies is highly heterogeneous in a homogeneous study population. These observations have implications for COVID-19 surveillance, vaccination strategies, and post-pandemic planning.