Carvacrol Alleviates Hyperuricemia-Induced Oxidative Stress and Inflammation by Modulating the NLRP3/NF-κB Pathwayt.

Muhammad RiazLina Tariq Al KuryNoreen AtzazAbdullah AlattarReem AlshamanFawad Ali ShahShupeng Li

Published in: Drug design, development and therapy (2022)

Carvacrol potentially alleviates hyperuricemia-induced oxidative stress and inflammation by regulating the ROS/NRLP3/NF-κB pathway, thereby exerting protective effects against joint degeneration.

Keyphrases

oxidative stress
signaling pathway
hydrogen peroxide
lps induced
uric acid
dna damage
pi k akt
nuclear factor
mouse model
cell death
inflammatory response
reactive oxygen species
nitric oxide
nlrp inflammasome