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IL-10 Deficiency Aggravates Renal Inflammation, Fibrosis and Functional Failure in High-Fat Dieted Obese Mice.

Dae Hwan KimSo Young ChunEun Hye LeeBomi KimBo Hyun YoonHaejung GilMan-Hoon HanYun Sok HaJun Nyung LeeTae Gyun KwonBum Soo KimByeong Ik Jang
Published in: Tissue engineering and regenerative medicine (2021)
IL-10 deficiency aggravates renal inflammation, fibrosis and functional failure in high-fat dieted obese mice, thus IL-10 therapy could be applied to obesity-related chronic renal failure.
Keyphrases
  • oxidative stress
  • type diabetes
  • insulin resistance
  • weight loss
  • replacement therapy
  • body mass index
  • mesenchymal stem cells