The functional epigenetic landscape of aberrant gene expression in molecular subgroups of newly diagnosed multiple myeloma.

Samrat Roy ChoudhuryCody AshbyRuslana TytarenkoMichael BauerYan WangShayu DeshpandeJudith DenCarolina SchinkeMaurizio ZangariSharmilan ThanendrarajanFaith E DaviesFrits van RheeGareth J MorganBrian A Walker

Published in: Journal of hematology & oncology (2020)

Therefore, this study presents the underlying epigenetic regulatory networks of gene expression dysregulation in NDMM patients and identifies potential targets for future therapies.

Keyphrases

gene expression
newly diagnosed
dna methylation
end stage renal disease
multiple myeloma
genome wide
ejection fraction
chronic kidney disease
prognostic factors
peritoneal dialysis
transcription factor
patient reported outcomes
climate change
human health