Dl-3-n-Butylphthalide Alleviates Secondary Brain Damage and Improves Working Memory After Stroke in Cynomolgus Monkeys.
Zimu JiangJiating WeiJiahui LiangWeixian HuangFubing OuyangChunyong ChenPingping LiSuhan CaoYuangui CaiJianle LiBaozi HuangJinsheng ZengYicong ChenPublished in: Stroke (2024)
Our findings indicate that NBP improves working memory by alleviating remote secondary neurodegeneration and neuroinflammation in the ipsilateral dorsal lateral prefrontal cortex and thalamus after MCAO in cynomolgus monkeys.
Keyphrases
- working memory
- prefrontal cortex
- transcranial direct current stimulation
- attention deficit hyperactivity disorder
- spinal cord
- cerebral ischemia
- oxidative stress
- traumatic brain injury
- neuropathic pain
- white matter
- minimally invasive
- deep brain stimulation
- lps induced
- cognitive impairment
- mouse model
- blood brain barrier
- inflammatory response
- brain injury