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Successful Treatment of Disseminated Fusariosis in a 15-Month-Old Boy With Refractory Acute Lymphoblastic Leukemia Using High-Dose Voriconazole.

Loizos PetrikkosMaria KourtiAngeliki StathiKondilia AntoniadiMirella AmpatzidouKalliopi StefanakiLevantia ZachariadouElias IosifidisEmmanuel RoilidesSophia Polychronopoulou
Published in: The Pediatric infectious disease journal (2024)
Appropriate diagnostic approach and timely administration of optimal antifungal therapy with VCZ were important for the successful treatment of disseminated fusariosis. Therapeutic drug monitoring, especially in <2-year-old children, is necessary to achieve sufficient drug exposure for optimal therapeutic response without toxicity.
Keyphrases
  • acute lymphoblastic leukemia
  • high dose
  • low dose
  • candida albicans
  • oxidative stress
  • stem cell transplantation
  • drug induced
  • electronic health record
  • replacement therapy