The associations of APP, PSEN1, and PSEN2 genes with Alzheimer's disease: A large case-control study in Chinese population.

Xuewen XiaoHui LiuLu ZhouXixi LiuTianyan XuYuan ZhuQijie YangXiaoli HaoYingzi LiuWeiwei ZhangYafang ZhouJun-Ling WangJinchen LiBin JiaoLu Shen Xinxin Liao

Published in: CNS neuroscience & therapeutics (2022)

Our study indicated that non-pathogenic variants in PSEN2 and APP may be involved in AD pathogenesis in the Chinese population.

Keyphrases

early onset
genome wide
cognitive decline
gene expression
transcription factor
bioinformatics analysis