Male and female breast cancer: the two faces of the same genetic susceptibility coin.
Susana Nunes SilvaBruno Costa GomesSaudade AndréAna FélixAntónio Sebastião RodriguesJosé RueffPublished in: Breast cancer research and treatment (2021)
In males, XRCC1 and TP53 variants, when in heterozygosity, seem to be related with lower susceptibility for BC, contrasting with higher susceptibility for a MUTYH variant in females. These findings may help to explain the difference in incidence of BC between the two sexes.