FRC-derived retinoic acid: The key to unlocking milky spots.

Published in: The Journal of experimental medicine (2023)

Milky spots of the omentum enable lymphocyte access to the peritoneal cavity. In this issue of JEM, Yoshihara and Okabe (2023. J. Exp. Med.https://doi.org/10.1084/jem.20221813) demonstrate how secretion of retinoic acid by fibroblastic reticular cells allows lymphocyte entry into milky spots and the peritoneal cavity.

Keyphrases

induced apoptosis
peripheral blood
cell cycle arrest
signaling pathway
endoplasmic reticulum stress
oxidative stress
pi k akt