Mutational variant allele frequency profile as a biomarker of response to immune checkpoint blockade in non-small cell lung Cancer.

Ruyun GaoNing LouLin LiTongji XiePuyuan XingLe TangJiarui YaoXiaohong HanYuan-Kai Shi

Published in: Journal of translational medicine (2024)

The mutational VAF profile is a promising biomarker for ICI therapy in NSCLC, with enhanced therapeutic stratification and management as a supplement to PD-L1 or TMB.

Keyphrases

small cell lung cancer
advanced non small cell lung cancer
mesenchymal stem cells
tyrosine kinase
smoking cessation