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Genetic Parameters of Somatic Cell Score in Florida Goats Using Single and Multiple Traits Models.

Rocío Jimenez-GranadoAntonio MolinaChiraz ZiadiManuel SanchezEva Muñoz-MejíasSebastián Demyda-PeyrásAlberto Menendez-Buxadera
Published in: Animals : an open access journal from MDPI (2022)
A total of 1,031,143 records of daily dairy control test of Spanish Florida goats were used for this study. The database was edited, and only the records of the first three lactations were kept. The final database contained 340,654 daily-test somatic cell counts from 27,749 daughters of 941 males and 16,243 goats. The evolution of this count in the last 14 years was analyzed following French and American international associations' criteria for the risk of mastitis in goats, and confirmed the slight increase in SCS in the last years and the importance of this problem (50% of dairy control tests show a risk of suffering mastitis). For the genetic analysis, the SCS records were log-transformed to normalize this variable. Two strategies were used for the genetic analysis: a univariate animal model for the SCS assuming that SCS does not vary throughout the parities, and a multi-character animal model, where SCS is not considered as the same character in the different parities. The heritabilities (h 2 ) were higher in the multiple traits models, showings an upward trend from the first to the third parity (h 2 between 0.245 to 0.365). The genetic correlations of the same trait, as well as between breeding values (GVs) between different parities, were different from unity. The breeding values (EBVs) obtained for both models were subjected to a PCA: the first eigenvector (λ1) explained most of the variations (between 74% to 90%), while the second λ2 accounted for between 9% to 20% of the variance, which shows that the selection will be proportionally favorable but not equivalent in all parities and that there are some variations in the type of response.
Keyphrases
  • genome wide
  • copy number
  • single cell
  • cell therapy
  • dna methylation
  • physical activity
  • gene expression
  • emergency department
  • adverse drug
  • stem cells
  • mesenchymal stem cells