Balancing the immune response in the brain: IL-10 and its regulation.

Diogo Lobo-SilvaGuilhermina M CarricheA Gil CastroSusana RoqueMargarida Saraiva

Published in: Journal of neuroinflammation (2016)

The regulation of IL-10 production by central nervous cells remains a challenging field. Answering the many remaining outstanding questions will contribute to the design of targeted approaches aiming at controlling deleterious inflammation in the brain.

Keyphrases

immune response
resting state
white matter
induced apoptosis
oxidative stress
cell cycle arrest
functional connectivity
cerebral ischemia
dendritic cells
multiple sclerosis
cell death
drug delivery