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Depletion of d- and l-asparagine in cerebrospinal fluid in acute lymphoblastic leukemia during PEGasparaginase therapy.

Leiah J BrigithaRob PietersEduard A StruysAbdellatif BakkaliInge M Van der Sluis
Published in: Pediatric blood & cancer (2022)
l-Asparagine is not a better parameter than total asparagine in CSF due to the negligible amount of d-asparagine in the CSF before and after PEGasparaginase treatment.
Keyphrases
  • cerebrospinal fluid
  • acute lymphoblastic leukemia
  • allogeneic hematopoietic stem cell transplantation
  • stem cells
  • bone marrow
  • chemotherapy induced