PHF21B overexpression promotes cancer stem cell-like traits in prostate cancer cells by activating the Wnt/β-catenin signaling pathway.

Qiji LiLiping YeWei GuoMin WangShuai HuangXinsheng Peng

Published in: Journal of experimental & clinical cancer research : CR (2017)

Our results revealed that PHF21B functions as an oncogene in prostate cancer, and may represent a promising prognostic biomarker and an attractive candidate for target therapy of prostate cancer.

Keyphrases

prostate cancer
cancer stem cells
radical prostatectomy
cell proliferation
stem cells
signaling pathway
genome wide
transcription factor
single cell
mesenchymal stem cells
smoking cessation