Mutant IDH and non-mutant chondrosarcomas display distinct cellular metabolomes.
Sinthu PathmanapanOlga IlkayevaJohn T MartinAdrian Kwan Ho LoeHongyuan ZhangGuo-Fang ZhangChristopher B NewgardJay S WunderBenjamin A AlmanPublished in: Cancer & metabolism (2021)
Overall, our findings suggest that IDH mutations induce global metabolic changes in chondrosarcomas and shed light on deranged metabolic pathways.